We are developing also methodologies to integrate the extracellular matrix-like nanotopographical features, fabricated by supersonic cluster beam deposition, into applications and cell culture devices. In the neuroscience framework, we established e.g. a procedure that enable us to design micropattern of nanotopographical films permissive for neuronal cell adhesion (and neuronal differentiation-fostering) on elsewhere antifouling cell-repellent surfaces.